Moreover, it was shown previously that there was no cross\reactivity with other rodent allergens and rodent food
Moreover, it was shown previously that there was no cross\reactivity with other rodent allergens and rodent food.10 A possible explanation for higher levels of rodent allergens in the mattress dust of pet owners could be pets transferring rodent allergens through their fur. mouse urinary allergens (MUA) and mouse urinary protein (MUP) 8, a specific pheromone\binding mouse allergen, were significantly higher in mattress samples of laboratory animal workers than in those of controls. Hair\covering caps used in animal facilities harboured large amounts of RUA and MUA, which correlated significantly with exposure measured by the personal sampling technique in the animal facility. Conclusions Occupational laboratory animal allergens are detectable in mattress dust of laboratory animal workers. Transfer of allergens via uncovered hair of animal workers is likely contributing to this phenomenon. This study stresses the importance of using hair caps to prevent spreading of occupational allergens. Occupational allergy against laboratory animals is a common problem among laboratory animal workers. The prevalence of laboratory animal allergy is reported to be 10C25%.1 Allergens of laboratory animals are potent sensitisers and small amounts can elicit symptoms in sensitised individuals. Moreover, there are also indications that reduction of exposure may lead to a decreased incidence of laboratory animal allergy.2,3,4 Methods for controlling exposure to laboratory animal allergens include the choice of bedding materials and adjustment of cage\changing processes, and the use of personal protective equipment.5 Despite the fact that the risk of developing laboratory animal allergy is Lecirelin (Dalmarelin) Acetate high and personal protective equipment is widely available, respiratory protection is not routinely used. Laboratory coats and protective gloves are widely used, SJ 172550 but the use of hair\covering caps and facemasks is mostly restricted to already sensitised individuals to prevent symptoms. Although direct contact with animals probably accounts for most of the airway exposure, a possibly underestimated route of exposure may be subsequent exposure to allergens transferred from the animal facility through hair, clothing and documents.5 It was shown for cat allergen that transfer can lead to exposure of individuals without direct contact with animals.6,7 Moreover, children of laboratory animal workers were shown to have an increased risk of developing laboratory animal allergy,8 suggesting that subsequent exposure also influences allergen loads in houses of laboratory animal workers and may sensitise family members. It has been suggested that allergens captured in human hair can play an important role in exposure to laboratory animal allergens outside the SJ 172550 animal facility. So far, evidence supporting the relevance of this route of publicity is normally scarce, but pet workers are usually advised to clean their locks after work to avoid contamination SJ 172550 of the house environment with occupational aeroallergens.5 The usage of hair\covering caps is another solution to prevent allergen transfer through human hair. Not surprisingly advice, regular usage of locks caps or cleaning locks after finishing function was a typical method in 20% from the lab pet services we examined in HOLLAND. By contrast, particular clothing was found in all services. We assessed the degrees of lab pet things that trigger allergies in the mattress dirt of lab pet workers and likened it with allergen concentrations in mattresses of handles who aren’t occupationally shown. The allergen insert on locks\covering caps utilized by lab pet workers was assessed to assess whether bring\over through the locks of workers could be a relevant path of allergen transfer. Furthermore, the allergen insert on locks\covering hats was weighed against the amount of airborne publicity as dependant on the non-public airborne\dirt sampling technique. Strategies Mattress examples Fifteen lab pet employees and SJ 172550 15 handles were asked to get dust samples off their mattresses and cushions. The handles and their companions had never caused lab pets or in SJ 172550 pet services, rather than had rats or mice as dogs. They included medical doctors, medical lab staff and.