To research the functional function of MATR3 in viral replication we depleted or over-expressed MATR3 in Jurkat cells and primary PBLs in the framework of HIV an infection. novel single-cell evaluation pipeline to recognize particular biomarkers of HIV permissiveness Sylvie Rato, Antonio Rausell, Miguel Munoz, Amalio Telenti, Angela Ciuffi O8 A capsid-dependent integration plan linking T cell activation to HIV-1 gene appearance Alexander Zhyvoloup, Anat Melamed, Ian Anderson, Delphine Planas, Janos Kriston-Vizi, Robin Ketteler, Chen-Hsuin Lee, Andy Merritt, Petronela Ancuta, Charles Bangham, Ariberto Fassati O9 Characterisation of brand-new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Trojan genome Anthony Rodari, Benoit Truck Driessche, Mathilde Galais, Nadge Delacourt, Sylvain Fauquenoy, Caroline Vanhulle, Anna Kula, Arsne Burny, Olivier Rohr, Carine Truck Lint O10 Tissue-specific dendritic cells modulate latent HIV-1 reservoirs Thijs truck Montfort differentially, Renee truck der Sluis, Dave Speijer, Ben Berkhout Program 4: RNA trafficking & product packaging O11 A book containing SIVagm build in African Green Monkeys needs an HIV-1 gene Simone Joas, Erica Parrish, Clement Wesley Gnanadurai, Edina Lump, Christina M. Strzel, Nicholas F. Parrish, Ulrike Sauermann, Katharina T?pfer, Tina Schultheiss, Steven Bosinger, Guido Silvestri, Cristian Apetrei, Nicholas Huot, Michaela Mller-Trutwin, Daniel GIBH-130 Sauter, Beatrice H. Hahn, Christiane Stahl-Hennig, Frank Kirchhoff O18 Reprogramming initiates mobilization of endogenous mutagenic Series-1, and SVA retrotransposons in individual induced pluripotent stem cells with implications for web host gene appearance Gerald Schumann, GIBH-130 Sabine Jung-Klawitter, Nina V. Fuchs, Kyle R. Upton, Martin Mu?oz-Lopez, Ruchi Shukla, Jichang Wang, Marta Garcia-Canadas, Cesar Lopez-Ruiz, Daniel J. Gerhardt, Attila Sebe, Ivana Grabundzija, Patricia Gerdes, Mouse monoclonal to CD18.4A118 reacts with CD18, the 95 kDa beta chain component of leukocyte function associated antigen-1 (LFA-1). CD18 is expressed by all peripheral blood leukocytes. CD18 is a leukocyte adhesion receptor that is essential for cell-to-cell contact in many immune responses such as lymphocyte adhesion, NK and T cell cytolysis, and T cell proliferation Sylvia Merkert, Andres Pulgarin, Anja Bock, Ulrike Held, Anett Witthuhn, Alexandra Haase, Ernst J. Wolvetang, Ulrich Martin, Zoltn Ivics, Zsuzsanna Izsvk, J. Garcia-Perez, Geoffrey J. Faulkner O19 NF-B activation induces appearance of individual endogenous particle and retrovirus creation Tara Hurst, Aris Katzourakis, Gkikas Magiorkinis Program 7a and b: Innate sensing & intrinsic immunity O20 Id from the phosphatase functioning on T592 in SAMHD1 during M/G1 changeover Kerstin Schott, Rita Derua, Janna Seifried, Andreas Reuter, Heike Schmitz, Christiane Tondera, Alberto Brandariz-Nu?ez, Felipe Diaz-Griffero, Veerle Janssens, Renate K?nig O21 Vpx overcomes a SAMHD1-separate stop to HIV change transcription that’s particular to resting Compact disc4 T cells Hanna-Mari Baldauf, Lena Stegmann, Sarah-Marie Schwarz, Maud Trotard, Margarethe Martin, Gina Lenzi, Manja Burggraf, Xiaoyu Skillet, Oliver We. Fregoso, Efrem S. Lim, Libin Abraham, Elina Erikson, Laura Nguyen, Ina Ambiel, Frank Rutsch, Renate K?nig, Baek Kim, Michael Emerman, Oliver T. Fackler, Oliver T. Keppler O22 The function of SAMHD1 in antiviral limitation and immune system sensing in the mouse Sabine Wittmann, Rayk Behrendt, Bianca Volkmann, Kristin Eissmann, Thomas Gramberg O23 T cells expressing GIBH-130 reduced limitation elements are infected in therapy na preferentially?ve HIV-1 individuals Sebastian Bolduan, Herwig Koppensteiner, Stefanie Regensburg, Ruth Brack-Werner, Rika Draenert, Michael Schindler O24 GIBH-130 cGAS-mediated innate immunity spreads through HIV-1 env-induced membrane fusion sites from contaminated to uninfected principal HIV-1 target cells Aurlie Ducroux, Shuting Xu, Aparna Ponnurangam, Sergej Franz, Angelina Malassa, Ellen Ewald, Christine Goffinet O25 Perturbation of innate RNA and DNA sensing by individual T cell leukemia virus type 1 oncoproteins Sin-Yee Fung, Ching-Ping Chan, Chun-Kit Yuen, Kin-Hang Kok, Chin-Ping Chan, Dong-Yan Jin O26 Induction and anti-viral activity of Interferon subtypes in HIV-1 infection Ulf Dittmer O27 Vpu-mediated counteraction of tetherin is normally a significant determinant of HIV-1 interferon resistance Dorota Kmiec, Shilpa Iyer, Christina Strzel, Daniel Sauter, Beatrice Hahn, Frank Kirchhoff O28 DNA fix protein Rad18 restricts HIV-1 and Series-1 life cycle Yasuo Ariumi, Mariko Yasuda-Inoue, Koudai Kawano, Satoshi Tateishi, Priscilla Turelli O29 Organic mutations in allow get away from post-translational regulation and toggle antiviral specificity Alex Compton, Nicolas Roy, Fran?oise Porrot, Anne Billet, Nicoletta Casartelli,.