In mammals, large tumor suppressor (Lats)1/2 serine/threonine kinase phosphorylates at multiple sites on YAP, including Ser127, resulting in cytoplasmic translocation from the nucleus1,5,6. or LKB1

Weak CYP3A inhibitors may be likely to possess minimal effect on naloxegol publicity in regular clinical make use of, whereas moderate CYP3A inducers might reduce